Motorists were urged to avoid the area of West Fort Street, between Washington and Cass.
Residents at a nursing home in Westland were briefly evacuated because of smoke in the building.
Detroit Police say a backpack near the McDonalds at Grand River and Schaefer looked suspicious, so patrons and employees were evacuated while the scene was investigated.
Police say the evacuation was “precautionary,” but could not disclose the reason behind it.
The evacuation was ordered early Friday morning after a chemical spill in a research lab.
Police have a suspect in custody in connection with a threat at Detroit’s New Center One building.
The situation unfolded Wednesday morning at Carlysle and Mayfair streets, near Outer Drive.
Employees at the Marathon Oil Refinery on Detroit’s southwest side were evacuated after a suspected gas leak was discovered.
Marathon Petroleum officials appeared before Detroit City Council’s Public Health and Safety Committee Monday to answer questions regarding the recent fire at the downriver oil refinery.
Detroit residents are calling for an emergency evacuation plan nearly a week after an explosion at an oil refinery on the city’s southwest side.