The organization outlined the flurry of moves on its Twitter account and said another move would be announced Tuesday.
The injuries constitute a blow to the AL Central-leading Tigers as they try to hold off Kansas City for the division lead.
In his last two starts, prized Tigers prospect Robbie Ray lasted a combined 7 1/3 innings and gave up a total of 12 earned runs on 15 hits.
Robbie Ray, a rookie filling in for 2013 ERA champion Anibal Sanchez, certainly made the most of his two starts in the big leagues.
Ray got a standing ovation when he left the game Tuesday night.
Alex Avila can understand how Astros batters struggled to hit Robbie Ray’s deceptive fastball; at times Avila struggled to catch it.
Tonight will be a night that Tigers pitcher Robbie Ray never forgets…
Ray will take the spot of 2013 ERA champion Anibal Sanchez, who is on the 15-day disabled list with a laceration on his middle finger.
General manager Dave Dombrowski knows many people will not like this trade.